Team Dana-Farber Lab Rats at the 2015 Geared Up for Kids bike ride
Team Dana-Farber Lab Rats walked, ran and biked to raise funds for children’s brain tumor research. Many thanks to Rick Bern for the photograph!
Archive for month: October, 2015
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.
In this month’s featured publication, Drs. Santagata, Ligon, and Beroukhim and colleagues published a study where they analyzed brain metastases for alterations in their genetic profiles. In about half of the cases they found different genetic alterations in the brain metastases when compared with the primary tumor site. This study showed that the genetically different brain metastases were not detected when a patient undergoes a primary tumor biopsy, suggesting that sequencing the primary tumor alone may miss substantial opportunities for targeted therapy.
